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Structural Biology

Revolutionize your structural biology research with our Analysis Service. Effortlessly submit your data, and our experts will decode it using cutting-edge algorithms. From protein structure prediction to molecular dynamics simulations, gain actionable insights to advance your studies. Simplify your structural biology research with our streamlined service.

1.Proteome Profiling:
What it is: Proteome profiling involves analyzing the entire proteome from complex samples, such as complete cells, tissues, and body fluids.
Methodology: We perform sample digestion using sequencing-grade trypsin or alternative proteolytic methods. The resulting trypsin-digested peptide samples are then analyzed using nano-flow LC-MS/MS.
Applications:

2.Protein Identification: Uncover as many peptides and proteins as possible.
Quantitative Proteomics: Reference information for high-throughput protein quantification.
Protein Modification Analysis: Insights into post-translational modifications.
Biogrithm’s Approach: Our spectral counting method provides protein relative abundances. Additionally, our HPLC sample fractionation systems enhance protein sequence coverage and detection dynamic range1.
Precision Medicine Biomarkers:
Why It Matters: Precision medicine relies on integrating targeted drugs with biomarkers for early and actionable clinical insights.
Our Expertise: Biogrithm develops and delivers proteomic tools, services, and disease biomarkers. We provide not just data but sophisticated bioinformatics, offering biological insights2.

3.Total Protein Profiling and PTMs:
Comprehensive Suite: Biogrithm offers a wide range of analytical methods suitable for all protein-related research, regardless of sample type or species.
Post-Translational Modifications (PTMs): We delve into critical PTMs, including phosphorylation, glycosylation, and acetylation, guiding translational research3.

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