Genomic Data Analysis
Unlock insights effortlessly with our genomic data analysis Service. Simply upload your data, and our experts decode it using advanced algorithms. Gain actionable insights for your research, from variant calling to pathway analysis. Revolutionize your approach to genomics with our streamlined service.
.png)
Introduction :
Bioinformatics plays a pivotal role in genomics, providing powerful tools and techniques for analyzing biological data, particularly genomic data. At Biogrithm, we specialize in cutting-edge Genomic Data Analysis services that empower researchers, clinicians, and pharmaceutical companies to extract meaningful insights from vast datasets. Let’s explore how our services stand out:
1.Whole Genome Sequencing (WGS):
WGS involves sequencing an individual’s entire genome, including both coding and non-coding regions1. It provides comprehensive genetic information and is commonly used in rare disease diagnosis, cancer research, and infectious disease detection.
At Biogrithm, our WGS service offers high-throughput, massively parallel sequencing, enabling precise variant detection across the entire genome.
2.Whole Exome Sequencing (WES):
WES focuses on protein-coding regions (exons) of the genome, which constitute less than 2% of the total genome but contain ~85% of known disease-related variants2.
Biogrithm’s WES service efficiently identifies coding variants, making it a cost-effective alternative to whole-genome sequencing.
3.Genome Finishing (Hi-C / Bionano):
Hi-C: This technique captures chromatin conformation, providing a 3D view of genome organization3. It helps resolve structural variations and interactions between distant loci.
Bionano Genomics: Bionano’s optical mapping platform enables high-resolution genome finishing, especially for complex genomes and structural variations4.
Biogrithm’s genome finishing services utilize these cutting-edge technologies to enhance genome assembly and annotation.
4.Genotyping By Seq (GBS):
GBS is a cost-effective method for genome-wide SNP discovery without prior knowledge of the genome sequence5. It’s particularly useful for plant and animal studies.
Biogrithm’s GBS service aids in SNP discovery, genotyping, and population studies.
5.Single Cell Genomics:
Single cell genomics reveals the genomic blueprints of individual cells, providing insights into biochemical properties, evolutionary histories, and biotechnological potential6.
Biogrithm’s single cell genomics services analyze individual cells’ DNA, RNA, and epigenetic profiles, unlocking cellular heterogeneity and disease mechanisms.
6.Exosomal DNA / cfDNA-Seq:
Exosomal DNA and cell-free DNA (cfDNA) sequencing focus on extracellular vesicles and free-floating DNA in bodily fluids.
Biogrithm’s service investigates exosomal and cfDNA content, aiding in cancer diagnostics, liquid biopsies, and personalized medicine.
Real-World Impact:
Biogrithm’s Genomic Data Analysis services have transformed research and clinical practice:
Drug Discovery: Identifying drug targets and predicting drug responses.
Cancer Genomics: Personalized treatment strategies based on tumor profiles.
Rare Disease Diagnosis: Detecting pathogenic variants in rare genetic disorders.
Testimonials:
“Biogrithm’s services revolutionized our research. Their expertise and tools are unmatched.” – Dr. Arulvel, Research Scientist
Conclusion:
Biogrithm’s Genomic Data Analysis services empower clients to unlock insights effortlessly. Whether it’s variant calling, pathway analysis, or comparative genomics, we’re committed to advancing healthcare through data-driven precision.